829 research outputs found

    Mathematically inspired approaches to face recognition in uncontrolled conditions: super resolution and compressive sensing

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    Face recognition systems under uncontrolled conditions using surveillance cameras is becom-ing essential for establishing the identity of a person at a distance from the camera and providing safety and security against terrorist, attack, robbery and crime. Therefore, the performance of face recognition in low-resolution degraded images with low quality against im-ages with high quality/and of good resolution/size is considered the most challenging tasks and constitutes focus of this thesis. The work in this thesis is designed to further investigate these issues and the following being our main aim: “To investigate face identification from a distance and under uncontrolled conditions by pri-marily addressing the problem of low-resolution images using existing/modified mathemati-cally inspired super resolution schemes that are based on the emerging new paradigm of compressive sensing and non-adaptive dictionaries based super resolution.” We shall firstly investigate and develop the compressive sensing (CS) based sparse represen-tation of a sample image to reconstruct a high-resolution image for face recognition, by tak-ing different approaches to constructing CS-compliant dictionaries such as Gaussian Random Matrix and Toeplitz Circular Random Matrix. In particular, our focus is on constructing CS non-adaptive dictionaries (independent of face image information), which contrasts with ex-isting image-learnt dictionaries, but satisfies some form of the Restricted Isometry Property (RIP) which is sufficient to comply with the CS theorem regarding the recovery of sparsely represented images. We shall demonstrate that the CS dictionary techniques for resolution enhancement tasks are able to develop scalable face recognition schemes under uncontrolled conditions and at a distance. Secondly, we shall clarify the comparisons of the strength of sufficient CS property for the various types of dictionaries and demonstrate that the image-learnt dictionary far from satisfies the RIP for compressive sensing. Thirdly, we propose dic-tionaries based on the high frequency coefficients of the training set and investigate the im-pact of using dictionaries on the space of feature vectors of the low-resolution image for face recognition when applied to the wavelet domain. Finally, we test the performance of the de-veloped schemes on CCTV images with unknown model of degradation, and show that these schemes significantly outperform existing techniques developed for such a challenging task. However, the performance is still not comparable to what could be achieved in controlled en-vironment, and hence we shall identify remaining challenges to be investigated in the future

    Enhancing face recognition at a distance using super resolution

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    The characteristics of surveillance video generally include low-resolution images and blurred images. Decreases in image resolution lead to loss of high frequency facial components, which is expected to adversely affect recognition rates. Super resolution (SR) is a technique used to generate a higher resolution image from a given low-resolution, degraded image. Dictionary based super resolution pre-processing techniques have been developed to overcome the problem of low-resolution images in face recognition. However, super resolution reconstruction process, being ill-posed, and results in visual artifacts that can be visually distracting to humans and/or affect machine feature extraction and face recognition algorithms. In this paper, we investigate the impact of two existing super-resolution methods to reconstruct a high resolution from single/multiple low-resolution images on face recognition. We propose an alternative scheme that is based on dictionaries in high frequency wavelet subbands. The performance of the proposed method will be evaluated on databases of high and low-resolution images captured under different illumination conditions and at different distances. We shall demonstrate that the proposed approach at level 3 DWT decomposition has superior performance in comparison to the other super resolution methods

    Construction of dictionaries to reconstruct high-resolution images for face recognition

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    This paper presents an investigation into the construction of over-complete dictionaries to use in reconstructing a super resolution image from a single input low-resolution image for face recognition at a distance. The ultimate aim is to exploit the recently developed Compressive Sensing (CS) theory to develop scalable face recognition schemes that do not require training. Here we shall demonstrate that dictionaries that satisfy the Restricted Isometry Property (RIP) used for CS can achieve face recognition accuracy levels as good as those achieved by dictionaries that are learned from face image databases using elaborate procedures

    Making the NET. Framework More Secure Depending on Architecture of NET. Framework and its Security Levels

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    The .NET Framework is a managed type-safe environment for application development and execution. The .NET Framework manages all aspects of your program's execution, it allocates memory for the storage of data and instructions, grants or denies the appropriate permissions to your application, initiates and manages application execution, and manages the reallocation of memory from resources that are no longer needed

    Prevalence and type distribution of high-risk Human Papillomavirus (HPV) in breast cancer : a Qatar based study

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    Human papillomavirus (HPV) has been implicated in the etiology of a variety of human cancers. Studies investigating the presence of high-risk (HR) HPV in breast tissue have generated considerable controversy over its role as a potential risk factor for breast cancer (BC). This is the first investigation reporting the prevalence and type distribution of high-risk HPV infection in breast tissue in the population of Qatar. A prospective comparison blind research study herein reconnoitered the presence of twelve HR-HPV types’ DNA using multiplex PCR by screening a total of 150 fresh breast tissue specimens. Data obtained shows that HR-HPV types were found in 10% of subjects with breast cancer; of which the presence of HPV was confirmed in 4/33 (12.12%) of invasive carcinomas. These findings, the first reported from the population of Qatar, suggest that the selective presence of HPV in breast tissue is likely to be a related factor in the progression of certain cases of breast cancer

    BRAFV600E hot spot mutation in thyroid carcinomas: first Moroccan experience from a single-institution retrospective study

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    Background: The incidence of thyroid cancer is increasing worldwide at an alarming rate. BRAFV600E mutation is described to be associated with a worse prognostic of thyroid carcinomas, as well as extrathyroidal invasion and increased mortality. Objective: To our knowledge, there are no reported studies neither from Morocco nor from other Maghreb countries regarding the prevalence of BRAFV600E mutation in thyroid carcinomas. Here we aim to evaluate the frequency of BRAFV600E oncogene in Moroccan thyroid carcinomas. Methods: In this Single-Institution retrospective study realized in the Anatomic Pathology and Histology Service in the Military Hospital of Instruction Mohammed V \u2018HMIMV\u2019 in Rabat, we report, using direct genomic sequencing, the assessment of BRAFV600E in 37 thyroid tumors. Results: We detected BRAFV600E mutation exclusively in Papillary Thyroid Carcinomas \u2018PTC\u2019 with a prevalence of 28% (8 PTC out 29 PTC). Like international trends, Papillary Thyroid Carcinomas \u2019PTC\u2019 is more frequent than Follicular Thyroid Carcinomas \u2018FTC\u2019 and Anaplastic Thyroid Carcinomas \u2018ATC\u2019 (29 PTC, 7 FTC and 1 ATC). Conclusion: Our finding gives to the international community the first estimated incidence of this oncogene in Morocco showing that this prevalence falls within the range of international trends (30% to 90%) reported in distinct worldwide geographic regions

    Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis

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    BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London

    Mutations in TOP3A Cause a Bloom Syndrome-like Disorder

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    Bloom syndrome, caused by biallelic mutations in BLM, is characterized by prenatal-onset growth deficiency, short stature, an erythematous photosensitive malar rash, and increased cancer predisposition. Diagnostically, a hallmark feature is the presence of increased sister chromatid exchanges (SCEs) on cytogenetic testing. Here, we describe biallelic mutations in TOP3A in ten individuals with prenatal-onset growth restriction and microcephaly. TOP3A encodes topoisomerase III alpha (TopIIIα), which binds to BLM as part of the BTRR complex, and promotes dissolution of double Holliday junctions arising during homologous recombination. We also identify a homozygous truncating variant in RMI1, which encodes another component of the BTRR complex, in two individuals with microcephalic dwarfism. The TOP3A mutations substantially reduce cellular levels of TopIIIα, and consequently subjects’ cells demonstrate elevated rates of SCE. Unresolved DNA recombination and/or replication intermediates persist into mitosis, leading to chromosome segregation defects and genome instability that most likely explain the growth restriction seen in these subjects and in Bloom syndrome. Clinical features of mitochondrial dysfunction are evident in several individuals with biallelic TOP3A mutations, consistent with the recently reported additional function of TopIIIα in mitochondrial DNA decatenation. In summary, our findings establish TOP3A mutations as an additional cause of prenatal-onset short stature with increased cytogenetic SCEs and implicate the decatenation activity of the BTRR complex in their pathogenesis

    Burden of musculoskeletal disorders in the Eastern Mediterranean Region, 1990–2013: findings from the Global Burden of Disease Study 2013

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    Moradi-Lakeh M, Forouzanfar MH, Vollset SE, et al. Burden of musculoskeletal disorders in the Eastern Mediterranean Region, 1990–2013: findings from the Global Burden of Disease Study 2013. Annals of the Rheumatic Diseases. 2017;76(8):annrheumdis-2016-210146
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